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Newborns (especially preterm) lack the ability to metabolize benzyl alcohol, leading to metabolic acidosis, respiratory distress, hypotension and (in reported cases) the often-fatal gasping syndrome. For this reason, only preservative-free sterile water (no benzyl alcohol) is used in pediatric or neonatal care
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The first freeze-thaw cycle causes 3050% potency loss through mechanical denaturation, and a second cycle compounds the damage to the point where the solution has negligible bioactivity
Drugs 81:963969 Dhillon S (2022) Tebentafusp: first approval
Each vial contains 10mg of lyophilized BPC-157 , prepared for advanced laboratory research applications
Sterile laboratory-grade water
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